COMPARATIVE EFFECTIVENESS OF LOCAL APPLICATION OF CHLORHEXIDINE GLUCONATE, MUPIROCIN OINTMENT, AND NORMAL SALINE FOR THE PREVENTION OF PERITONEAL DIALYSIS-RELATED INFECTIONS (COSMO-PD TRIAL): A MULTICENTER RANDOMIZED, DOUBLE-BLIND, CONTROLLED PROTOCOL

Comparative Effectiveness of Local Application of Chlorhexidine Gluconate, Mupirocin Ointment, and Normal Saline for the Prevention of Peritoneal Dialysis-related Infections (COSMO-PD Trial): a multicenter randomized, double-blind, controlled protocol

Abstract Background Current international guidelines recommend the use of a daily topical exit-site antimicrobial to prevent peritoneal dialysis (PD)-related infections.Although nonantibiotic-based therapies are appealing because they may limit antimicrobial resistance, no Pentair IntelliBrite 5G Parts controlled trials have been conducted to compa

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Aggregated clumps of lithistid sponges: a singular, reef-like bathyal habitat with relevant paleontological connections.

The advent of deep-sea exploration using video cameras has uncovered extensive sponge aggregations in virtually all oceans.Yet, a distinct type is herein reported from the Mediterranean: a monospecific reef-like formation built by the lithistid demosponge Leiodermatium pfeifferae.Erect, plate-like individuals (up to 80 cm) form bulky clumps, making

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Mechanisms and therapeutic actions of edible fruits in inflammatory bowel disease: A review of pre-clinical studies

The review highlights the significance of traditional knowledge in using edible fruits to address health issues, specifically focusing on inflammatory bowel disease (IBD).Edible fruits are rich in beneficial components like dietary fiber, vitamins, minerals, polyphenols, bioactive peptides, and antioxidants which contribute to overall health and sh

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